Non-invasive Diagnosis of Invasive Pulmonary Aspergillosis by Use of Biomarkers in Exhaled Breath… (NCT04358419) | Clinical Trial Compass
CompletedNot Applicable
Non-invasive Diagnosis of Invasive Pulmonary Aspergillosis by Use of Biomarkers in Exhaled Breath Condensate
Denmark101 participantsStarted 2020-04-17
Plain-language summary
In this study, a new, non-invasive method for diagnosis of pulmonary aspergillosis (PA) will be tested in a clinical pilot project.
Who can participate
Age range18 Years
SexALL
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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Suspected/confirmed PA patients:
* Hospitalized or ambulatory patients with a suspected PA at Aalborg University Hospital.
* Are conscious and able to understand the given study information.
* Possess legal capacity.
* Age above 18 years.
* Informed, signed consent is obtained.
* Clinically stable, which is defined as patients with stable blood pressure and not in need for other treatments.
* No need for organ support, which comprises need for vasopressors or inotropes, mechanical ventilation, extra corporal circulation or renal replacement therapy.
* Controls
• Patients as the PA patients, but where the diagnosis of PA is rejected will be included as controls.
* Suspected/confirmed pneumocystis pneumonia patients:
* Hospitalized or ambulatory patients with a suspected pneumocystis pneumonia at Aalborg University Hospital - chest x-ray must support the tentative diagnosis of pneumocystis pneumonia.
* Are conscious and able to understand the given study information.
* Possess legal capacity.
* Age above 18 years.
* Informed, signed consent is obtained.
* Clinically stable, which is defined as patients with stable blood pressure and not in need for other treatments.
* No need for organ support, which comprises need for vasopressors or inotropes, mechanical ventilation, extra corporal circulation or renal replacement therapy.
* Controls
• Patients as the pneumocystis pneumonia patients, but where the diagnosis is rejecte…
What they're measuring
1
Identification of Aspergillus proteins in the EBC from patients with proven/probable/possible PA