CompletedPhase 2

Management of Ovarian Hyperstimulation Syndrome as a State of Defective Mineralocorticoid Response

Egypt107 participantsStarted 2019-04-01

Plain-language summary

lines of evidence that support nature of ovarian hyperstimulation syndrome (OHSS) as "defective mineralocorticoid response" are cited, our hypothesis is tested clinically in both prophylaxis against and treatment of OHSS.

Who can participate

Age range18 Years – 40 Years

SexFEMALE

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: patients undergoing ICSI who were considered at risk of developing OHSS: * polycystic ovaries and/or previous history of OHSS, AMH \> 40 pmol/L but patients were finally included in the study if serum E2 levels reached \>3000 pg/ml on day of hCG trigger or at any stage of folliculometry * age: 18-40 Exclusion Criteria: * retrieval of less than 20 oocytes * age less than 18 or above 40

What they're measuring

duration of recovery

Timeframe: 10 days

prevention of OHSS occurrence

Timeframe: 21 days

Trial details

NCT IDNCT04351126

SponsorGanin Fertility Center

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2020-02-25

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