Quantifying the Epidemiological Impact of Targeted Indoor Residual Spraying on Aedes-borne Diseases

Inclusion Criteria: Household Level Inclusion Criteria: * Household is located within the bounds of a study cluster (5x5 city-block clusters) * City block has at least 60% premises that are residential Individual Level Inclusion Criteria: * 2 or more and up to 15 years of age at the time of initial enrollment * Living in a house that consented to TIRS (for children in TIRS cluster) Exclusion Criteria: Household Level Exclusion Criteria: * Households where study personnel identify a security risk (i.e., site where drugs are sold, residents are always drunk or hostile) * Sites where no residents spend time during the day (i.e. work 7days a week outside the home) * Inability for a resident to provide informed consent * Non-residential places (e.g., businesses, schools, markets, etc.) Individual Level Exclusion Criteria: * Less than 2 years of age or more than 15 years of age at the time of enrollment * Not living in a house that consented to TIRS (for children in TIRS cluster) * Having a medical condition that prevents implementation of study procedures * Temporary visitor to household * Plans to leave study area within next 12 months