Improved survival of very preterm newborn population during the last decades has challenged us neonatologists to study and improve nutritional practices including vitamin D (VitD) supplementation. However, long term outcome in this aspect has not been researched in well documented preterm populations. As VitD has receptors in almost all human cells it modulates growth of many organs. Therefore I start to assess VitD supplementation practices and later health outcome (bones, teeth, muscles, heart, lungs) in two preterm population cohorts cared in Oulu University Hospital at the age of 5 years and 24 years (born 2014-2017 and 1994-1997).
Age range
5 Years – 25 Years
Sex
ALL
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Vitamin D of preterm adults, before = VitD 0A
Timeframe: Baseline
Vitamin D of preterm children = VitD C
Timeframe: Baseline
Vitamin D of preterm adults, after = VitD 1A
Timeframe: One year
Exercise heart rate, before = HR 0A
Timeframe: Baseline
Exercise heart rate, after = HR 1A
Timeframe: One year
HRV of preterm adults, before = HRV 0A
Timeframe: Baseline
HRV of preterm adults, after = HRV 1A
Timeframe: One year
HRV of preterm children = HRV 0C
Timeframe: Baseline
Lung reversibility test in preterm adults, before = LR 0
Timeframe: Baseline
Lung function capacity in preterm adults, before = LFC 0
Timeframe: Baseline
Lung function volume in preterm adults, before = LFV 0
Timeframe: Baseline
Lung function capacity in preterm adults, after = LFC 1
Timeframe: One year
Lung function volume in preterm adults, after = LFV 1
Timeframe: One year
Lung function in preterm children
Timeframe: Baseline
Body composition of bone mineral density in preterm adults, before = BMD 0A
Timeframe: Baseline
Body composition of bone mineral content in preterm adults, before = BMC 0A
Timeframe: Baseline
Body composition of bone mineral density in preterm children = BMD C
Timeframe: Baseline
Body composition of bone mineral content in preterm children = BMC C
Timeframe: Baseline
Body composition of bone mineral density in preterm adults, after = BMD 1A
Timeframe: One year
Body composition of bone mineral content in preterm adults, after = BMC 1A
Timeframe: One year