CompletedPhase 1/2

Adipose Tissue Derived Stromal Vascular Fraction (SVF) Application in Treatment of Long Bones Nonunion

India11 participantsStarted 2019-11-10

Plain-language summary

Nonunion is a major complication of fractures.Per cutaneous bone marrow concentrate (BMC) application around fracture ends is being utilized with great success . Mesenchymal Stem Cells (MSCs)are one of the major cell types found in BMC responsible for results Adipose tissue is an alternative source for MSCs. Besides abundant and readily accessible it also overcomes issue of morbidity with bone marrow aspiration. this retrospective analysis to report the outcome in patients treated with fluoroscopic guided percutaneous injection of SVF at the site of fracture as an outpatient procedure between November 2012 to August 2018.

Who can participate

Age range25 Years – 70 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Non-union or delayed union diagnosed after x-ray examination More than 4 cm distance from the joint Exclusion Criteria: * Multiple major fracture or untreated major fracture * Infected fracture * HIV, hepatitis B or hepatitis C infection at the time of screening * Diagnosis of cancer * Active treatment with immunosuppressive drugs or anticoagulant agents * Known allergic reaction to components of study treatment and/or study injection

What they're measuring

Union

Timeframe: 8 weeks

Trial details

NCT IDNCT04340284

SponsorDr. Himanshu Bansal Foundation

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2020-02-14

View on ClinicalTrials.gov More Nonunion of Fracture trials