Telehealth CBT for Adolescents and Young Adults With Childhood-onset Systemic Lupus Erythematosus

Inclusion Criteria: * Participants must be diagnosed with cSLE, meeting the revised American College of Rheumatology Classification Criteria for SLE by age 18 years * Participants must have at least one elevation (based off of screening measures) in fatigue, or depressive symptoms, or pain * Patient participants must have English language proficiency * For participants under age 18, must have a primary caregiver willing to participate. Exclusion Criteria: * Patients with other chronic medical conditions (e.g., juvenile arthritis), * Patients with a documented developmental delay, severe cognitive impairment, or thought disorder * Patients with an untreated major psychiatric illness (e.g., bipolar disorder, psychosis, severe depression, or active suicidal ideation) * Patients currently receiving psychological treatment for depression, fatigue or pain will be excluded to prevent overlapping treatments that may confound outcomes.