International Swiss Primary Hypersomnolence and Narcolepsy Cohort Study

Inclusion Criteria: Study participants: * Subjective complaints of Excessive daytime sleepiness (EDS) and/or Hypersomnia (H) as defined above * EDS and/or H present daily or almost daily for at least 1 month prior to the consultation * Ability and consent to undergo electrophysiological routine assessment * Ability to give informed consent Healthy controls: * Age and gender matched healthy subjects * Including blood related relatives of study participants * Ability and consent to undergo electrophysiological routine assessment * Ability to give informed consent Controls with Sleep disordered breathing (SDB): * Subjective complaints of EDS with Epworth Sleepiness Scale (ESS) \> 10 (adults) and/or H due to SDB: Presence of clinically significant and untreated obstructive sleep apnea (OSA) as determined by the investigator with an apnea-hypopnea-index \>30/h * Multiple sleep-latency test (MSLT) mean sleep latency ≤ 8min * Subjective and objective improvement of EDS and/or H within 3 months after treatment with * Positive airway pressure (PAP) therapy with documented * Reduction of apnea-hypopnea index below \<10/h * Reduction of ESS by ≥ 25% * MSLT mean Sleep Latency \> 12min * Ability and consent to undergo electrophysiological routine assessment * Ability to give informed consent Exclusion Criteria: Study participants and controls: * SDB for study participants and healthy controls: Presence of clinically significant and untreated obstructive sleep apnea (OSA) o…