The study aims to examine a behavioral and neural framework for understanding the sex-specific effects of the neuropeptide oxytocin (OXT). Using hormonal, behavioral and neuroimaging readouts, it is planned to explore the interplay of OXT and estradiol as a potential mechanism mediating sexual dimorphic effects.
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Electrodermal responses to fear-conditioned stimuli
Timeframe: 3 hours after gel administration and 30 minutes after nasal spray administration
Emotion recognition thresholds
Timeframe: 200 minutes after gel administration and 50 minutes after nasal spray administration
Resting state functional connectivity
Timeframe: 3 hours after gel administration and 30 minutes after nasal spray administration
Neural responses to emotional faces
Timeframe: 190 minutes gel administration and 40 minutes after nasal spray administration
Neural responses to an emotional subsequent memory task
Timeframe: 200 minutes after gel administration and 50 minutes after nasal spray administration