CompletedNot Applicable

The Broken Heart Study II (BHS-II)

United States66 participantsStarted 2020-09-02

Plain-language summary

The goals of this study are as follows: 1. To rigorously establish and characterize heterogeneity in the pathophysiology of Takotsubo Syndrome (TS). 2. To rigorously test the contribution of TS triggering events and mental stress responsiveness to 1-year prognosis after TS event.

Who can participate

Age range18 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Age \>=18 * A new diagnosis of takotsubo syndrome fulfilling Mayo Clinic criteria * Ability to understand and speak English Exclusion Criteria: * Inability or unwillingness to give informed consent * Severe cognitive impairment * Uncontrolled hypertension * Acute psychosis * High suicidal risk * Pregnancy * Poor echocardiographic window * Conditions that would interfere with adherence to study requirements (e.g., ongoing alcohol or substance abuse) * If the participant is clinically unstable

What they're measuring

Mean change (in pg/mL) in plasma epinephrine levels

Timeframe: Up to 4 weeks

Mean change (in pg/mL) in plasma norepinephrine levels

Timeframe: Up to 4 weeks

Trial details

NCT IDNCT04325321

SponsorThe Miriam Hospital

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2025-11-11

View on ClinicalTrials.gov More Takotsubo Cardiomyopathy trials