CompletedPhase 4

Radiographic and Histological Evaluation of Regenerated Bone After Grafting Using Allograft Shell and Autogenous Chips

Egypt10 participantsStarted 2018-04-08

Plain-language summary

The clinical cases in the present study described the khoury shell technique using an allograft plate and autogenous chips, for horizontal reconstruction of the anterior alveolar ridge in the esthetic zone. Without need to use autogenous bone graft techniques that are characterized by more aggressive surgery.

Who can participate

Age range

18 Years – 50 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Patients with class IV of Cawood and Howell classification in the anterior maxilla. * Males and females 18-50 years of age. * Patients with adequate oral hygiene. * Patients with healed sites for at least 6 months after tooth extraction. * Patients with an inter-arch distance of at least 6 mm. * Compliance with all requirements in the study and signing the informed consent. Exclusion Criteria: * Patients with diseases of the immune system or systemic disease affecting bone healing * Patients who are chronic users of medications known to affect the periodontal status. * Patients with history of intravenous and/or oral bisphosphonate use. * Pathologic lesions or acute infection in the area of defect. * Patients who are pregnant or lactating mothers. * Heavy smokers who smoke more than 10 cigarettes a day. * Patients with poor oral hygiene that are not amenable to motivation and improvement. * Patients with history of irradiation of the head and neck region. * Vulnerable patients.

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

Alveolar Bone quantity

Timeframe: 6 months

Trial details

NCT IDNCT04324697

SponsorOctober 6 University

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2019-07-01

View on ClinicalTrials.gov More Alveolar Bone Resorption trials