CompletedNot Applicable

Impact of Bladder Depletion on Mesorectal Movements During Radiotherapy in Rectal Cancer

France63 participantsStarted 2020-09-08

Plain-language summary

This trial is assessing how Bladder filling variations and thus mesorectal movements are less when radiotherapy treatment is received with an empty bladder in rectal cancer

Who can participate

Age range18 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Histologically confirmed rectal adenocarcinoma * T2 N+ or T3 any N, eligible for radiotherapy or neo-adjuvant radio-chemotherapy treatment in a long course of 25 fractions * Performance Status less or equal to 2 * Male or female 18 Years and older * Creatinine clearance greater than or equal to 50ml/min * Fertile patients must use effective contraception * Written informed consent * Patient must be affiliated to a Social Health Insurance Exclusion Criteria: * Previous treatment with pelvic radiotherapy * Chronic inflammatory bowel disease in flare-up. * Urinary catheterization, urinary diversion or cystectomy * Hip prosthesis * History of prostatectomy, or hysterectomy * Urinary incontinence \> 2 * Pregnant or nursing patient * Persons deprived of their liberty, as well as adults subject to a legal protection measure * Impossibility to submit to the medical follow-up of this clinical trial for geographical, social or psychological reasons

What they're measuring

Evaluate using imaging techniques and dosimetric analysis the performance of empty versus filled bladder radiotherapy treatment

Timeframe: 3.5 years

Evaluate using imaging techniques and dosimetric analysis the performance of empty versus filled bladder radiotherapy treatment

Timeframe: 3.5 years

Trial details

NCT IDNCT04323722

SponsorInstitut Cancerologie de l'Ouest

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2024-09-11

View on ClinicalTrials.gov More Rectal Cancer trials

Who can participate

Age range18 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.