THRIVE (Transnasal Humidified Rapid-Insufflation Ventilatory Exchange) refers to the use of high-flow nasal cannula to augment the ability to oxygenate and ventilate a patient under general anesthesia. The use of high-flow nasal cannula oxygen supplementation during anesthesia for surgical procedures has been a recent development in the adult population, with limited data analyzing the pediatric population. This study will determine whether high flow nasal cannula oxygen supplementation during surgical or endoscopic procedures can prevent desaturation events in children under anesthesia and improve the outcomes of that surgery.
Age range
18 Years
Sex
ALL
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The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
Number of Participants With 4% Decrease From Baseline in Oxygen Desaturation Index
Timeframe: Duration of surgery or procedure, which is generally less than 2 hours
Number of Participants With Desaturations <90%
Timeframe: Duration of surgery or procedure, which is generally less than 2 hours
Number of Participants Who Ever Either Fall Below 90% O2 or Drop 4% Below Baseline Saturation
Timeframe: Duration of surgery or procedure, which is generally less than 2 hours