CompletedNot Applicable

Prevalence of Hypoglycaemia in Congenital Adrenal Insufficiency

France9 participantsStarted 2020-07-15

Plain-language summary

Children with congenital primary and secondary adrenal insufficiency, who are deficient in cortisol, are at risk for hypoglycaemia, irrespective of appropriate hydrocortisone treatment, which can lead to potentially serious neurological complications. Few series are described in pediatrics. The prevalence of hypoglycaemia is probably underestimated because it is often asymptomatic and capillary blood glucose monitoring is not always performed routinely. The objective of the study is to evaluate the prevalence of hypoglycaemia in children with adrenal insufficiency.

Who can participate

Age range6 Months – 6 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * All male and female patients, followed in the Paediatric Endocrinology Department at Necker Hospital, with congenital primary and secondary adrenal insufficiency. * Age between 6 months and 6 years. * Included in the social security system. * Parental consent and willingness to participate in this study: involves training and skills in the use of blood glucometers. Exclusion Criteria: * Patients with acquired adrenal insufficiency. * Patients with type 1 or type 2 diabetes. * Patients with somatotropic deficiency associated with adrenal insufficiency. * Refusal or impossibility to perform the glycaemic measurements according to the procedure of the study. * Not covered by the social security system.

What they're measuring

Prevalence of hypoglycaemia

Timeframe: 1 year

Trial details

NCT IDNCT04322435

SponsorAssistance Publique - Hôpitaux de Paris

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2022-08-31

View on ClinicalTrials.gov More Adrenal Insufficiency, Congenital trials