Topical Chamomile in Preventing Chemotherapy-induced Oral Mucositis

Inclusion Criteria: * Patients who are going to receive 5-Fluoroucil (5-FU) based chemotherapy regime. Males and females with an age of not less than 20 years and not exceeding 70 years. Exclusion Criteria: * 1\. Patients suffering from any uncontrolled systemic diseases that affect integrity of the epithelium (such as diabetes, cardiovascular, liver disorder and renal dysfunction) 2. Pregnant and lactating women 3. Patients with findings of any physical or mental abnormality which would interfere with or be affected by the study procedure