Pregnancy Outcomes and Maternal Insulin Sensitivity

Inclusion Criteria: * Healthy singleton pregnant women (10-12 weeks of gestation) * BMI ≥25 kg/m2 * FPG ≤7.0 mmol/l * Dutch or English speaking * Written informed consent Exclusion Criteria: * Serious health complications (Hypertension, Hyperlipidemia, Asthma, Haemochromatosis) or medication use that influence the glucose metabolism or fetal growth (e.g. corticosteroids). * Multiple pregnancy * pre-existing Diabetes type 1 and 2 defined as FPG ≥7.0 mmol/l or use of diabetes medication * Participation in any other studies involving the investigation of medication or nutritional products or severe illness or antibiotic use in the two weeks prior to entry into the study * HIV/Hepatitis * Expectation of non-compliance to the study protocol, among others, a fear of needles * Known allergies or intolerances for one or more nutritional ingredients in the MTT * Psychological dysfunctions