WithdrawnNot Applicable

T-MACS Decision Aid: a Randomized, Controlled Point of Care Trial

Stopped: CI no longer wishes to complete this study due to Covid-19

United Kingdom0Started 2021-01

Plain-language summary

The aim of the study is to establish whether the safety of the T-MACS decision aid to immediately 'rule out' acute coronary syndromes with one blood sample for the cardiac damage marker troponin, is non-inferior to an approach requiring serial troponin sampling over three hours.

Who can participate

Age range18 Years – 100 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * \>18 years of age * Presents to the Emergency Department with pain, discomfort or pressure in the chest, epigastrium, neck, jaw, or upper limb without an apparent non-cardiac source which the treating physician believes warrants investigation for possible acute coronary syndrome * The patient is identified as being at 'very low risk' by the T-MACS decision aid following a single hs-cTn test at the time of arrival in the Emergency Department Exclusion Criteria: * No capacity to provide informed consent * Inability to communicate in English language if translation services are unavailable * Patient is a prisoner * No NHS number (precluding electronic follow up)

What they're measuring

The incidence of major adverse cardiac event

Timeframe: 30 days

Trial details

NCT IDNCT04313465

SponsorManchester University NHS Foundation Trust

Sponsor typeOTHER_GOV

Study typeINTERVENTIONAL

Primary completion2021-06

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