TerminatedPhase 2

NO Prevention of COVID-19 for Healthcare Providers

Stopped: COVID wave passed and we closed the study prematurely

United States24 participantsStarted 2020-04-07

Plain-language summary

Thousands of healthcare workers have been infected with SARS-CoV-2 and contracted COVID-19 despite their best efforts to prevent contamination. No proven vaccine is available to protect healthcare workers against SARS-CoV-2. This study will enroll 470 healthcare professionals dedicated to care for patients with proven SARS-CoV-2 infection. Subjects will be randomized either in the observational (control) group or in the inhaled nitric oxide group. All personnel will observe measures on strict precaution in accordance with WHO and the CDC regulations.

Who can participate

Age range18 Years – 99 Years

SexALL

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Inclusion criteria

✓. Age ≥18 years
✓. Scheduled to work with SARS-CoV-2 infected patients for at least 3 days in a week.

Exclusion criteria

✕. Previous documented SARS-CoV-2 infections and subsequent negative SARS-CoV-2 rt-PCR test.
✕. Pregnancy
✕. Known hemoglobinopathies.
✕. Known anemia

What they're measuring

COVID-19 Diagnosis

Timeframe: 14 days

Trial details

NCT IDNCT04312243

SponsorMassachusetts General Hospital

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2022-01-10

Results submitted2026-02-10

View on ClinicalTrials.gov More Coronavirus Infections trials