Long-term Prognosis of Patients With Hepatitis B Related Acute-on-chronic Liver Failure

Inclusion Criteria: * Age from 18 to 65 years old; * The diagnosis consistent with hepatitis b associated chronic acute liver failure； * After hospitalization, the survival time \> 90 days； * The inpatient clinical data are complete. Exclusion Criteria: * Human immunodeficiency virus infection or congenital immune deficiency diseases; * Liver cancer and other tumors, autoimmune liver disease, genetic and metabolic liver disease, or other serious diseases that significantly affect patient survival; * Other conditions that the researchers judged not appropriate for inclusion.