Analysis of MicroBial Metabolites After Eating Refined Food

Inclusion Criteria: * Men and women age 18 years or above. * Able to provide informed consent and comply with study protocol * Able to remain on a stable aspirin regimen (either on or off aspirin or aspirin products) for 1 week prior to starting study until the end of the study period. Exclusion Criteria: * Significant chronic illness or end-organ dysfunction, including known history of uncompensated heart failure, renal failure, pulmonary disease, hematologic diseases. * Active infection or received antibiotics within 6 months of study enrollment. * Use of over-the-counter probiotic within past month. * Chronic gastrointestinal disorders. * Intolerance to probiotic therapy. * Allergy to vancomycin, ciprofloxacin, neomycin, metronidazole, or lactose. * Allergy to any of the food components of the challenge meals. * Having undergone bariatric procedures or surgeries such as gastric banding or bypass. * Pregnancy.