UnknownNot Applicable

Management of Prelabor Rupture of the Membranes at Term

Israel524 participantsStarted 2020-05-01

Plain-language summary

Prolonged rupture of membranes has been associated with increased risk of chorioamnionitis and endometritis. In this study the investigators will investigate whether an early intervention to augment labor with oxytocin is superior to expected management for spontaneous delivery (up to 24 hours).

Who can participate

Age range18 Years – 45 Years

SexFEMALE

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Inclusion criteria

✓. Primiparous women with a singleton pregnancy that are admitted with prelabor rupture of membranes.
✓. Women at gestational age 370/7 or more.
✓. Vertex presentation.

Exclusion criteria

✕. Age 18 and under.
✕. High order gestation.
✕. Women with contraindication for a vaginal delivery.
✕. Active labor.
✕. Documented fetal anomalies.
✕. Known or suspected intrauterine infection (temperature \> 38 degrees, leucocytosis).
✕. Non reassuring fetal heart rate tracing.
✕. Positive group B streptococcus status.

What they're measuring

Maternal infectious morbidity

Timeframe: Up to 48 hours postpartum

Trial details

NCT IDNCT04307069

SponsorRambam Health Care Campus

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2024-05-01

Contact for this trial

Gal Bachar, MD

+972524858699 gal.bachar13@gmail.com

View on ClinicalTrials.gov More Fetal Infection trials