CompletedNot Applicable

Do Heat and Moisture Exchange Mask Reduce EIB and Cough Severity in Asthma

26 participantsStarted 2016-09-01

Plain-language summary

The overall aim of this study is to determine if face masks that can warm and humidify air can improve overall asthma control and markers of airway health during exercise in cold dry environments. We will investigate the potential protective benefits of the face masks against exercise induced asthma during 1) a "one-off" bout of exercise in a cold dry environment and 2) over the course of a four week period, exercising three times per week in a cold dry environment.

Who can participate

Age range

18 Years – 45 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Ability to consent to the research * Prior clinician based diagnosis of asthma * Males and females * 18 - 45 years * Engage in regular exercise (at least twice weekly) * Normal resting Forced Expiratory Volume in One Second (FEV1); defined as greater than 80% of predicted value. Exclusion Criteria: * Chest infection within the past 4 weeks, or any other illness within the past 2 weeks * Fall in FEV1 \>50% from baseline following exercise challenge (see protocol) * Baseline FEV1 of \< 80% of predicted * Cardiovascular conditions: * Coronary Artery Disease * High Blood Pressure * Heart Failure * Diagnosed Abnormality of Heart Rhythm * Metabolic diseases: * Type 1 diabetes * Type 2 diabetes * Pre-diabetes * Daily use of oral corticosteroids * Hospitalisation due to asthma in the six months prior to study commencement * Injury or conditions that limit mobility * Pregnancy

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

% fall in FEV1

Timeframe: 30 minutes

Trial details

NCT IDNCT04302610

SponsorUniversity of Kent

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2018-04-01

View on ClinicalTrials.gov More Asthma, Exercise-Induced trials