CompletedNot Applicable

Do Heat and Moisture Exchange Mask Reduce EIB and Cough Severity in Asthma

26 participantsStarted 2016-09-01

Plain-language summary

The overall aim of this study is to determine if face masks that can warm and humidify air can improve overall asthma control and markers of airway health during exercise in cold dry environments. We will investigate the potential protective benefits of the face masks against exercise induced asthma during 1) a "one-off" bout of exercise in a cold dry environment and 2) over the course of a four week period, exercising three times per week in a cold dry environment.

Who can participate

Age range18 Years – 45 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Ability to consent to the research * Prior clinician based diagnosis of asthma * Males and females * 18 - 45 years * Engage in regular exercise (at least twice weekly) * Normal resting Forced Expiratory Volume in One Second (FEV1); defined as greater than 80% of predicted value. Exclusion Criteria: * Chest infection within the past 4 weeks, or any other illness within the past 2 weeks * Fall in FEV1 \>50% from baseline following exercise challenge (see protocol) * Baseline FEV1 of \< 80% of predicted * Cardiovascular conditions: * Coronary Artery Disease * High Blood Pressure * Heart Failure * Diagnosed Abnormality of Heart Rhythm * Metabolic diseases: * Type 1 diabetes * Type 2 diabetes * Pre-diabetes * Daily use of oral corticosteroids * Hospitalisation due to asthma in the six months prior to study commencement * Injury or conditions that limit mobility * Pregnancy

What they're measuring

% fall in FEV1

Timeframe: 30 minutes

Trial details

NCT IDNCT04302610

SponsorUniversity of Kent

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2018-04-01

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