Appetite and Exercise in Breast Cancer Survivors

Inclusion Criteria: * Female sex * Age: 18 - 45 years, since older age may impact appetite regulation45-47 and women \>45 are more likely to have begun the menopausal transition (estrogen relates to appetite and eating behavior) * Body mass index \[BMI\]: 25 - 35 kg/m2. Since body composition and body mass relate to appetite regulation and energy intake, a narrow BMI range should decrease heterogeneity within the results. The BMI range was chosen to represent a population at risk for developing obesity and associated comorbidities, while also excluding individuals with severe obesity (which may plausibly significantly impact energy intake regulation). * Pre-menopausal before cancer diagnosis and treatment * \<1 hour/week of planned physical activity by self-report in the previous 12 months, since exercise may alter appetite and response to food * Diagnosis of primary stage I - II estrogen receptor/progesterone receptor-positive (ER/PR+) breast cancer, according to institutional standards. * All chemotherapy, radiation, and surgery completed at least two weeks (14 days), but less than 6 months prior to registration Exclusion Criteria: * Cancer diagnosis in the last 5 years before breast cancer; any site, excluding melanoma * History of cardiovascular disease or symptoms suggestive of cardiovascular disease: chest pain, shortness of breath at rest or with mild exertion, syncope * Diabetes mellitus, uncontrolled hypertension (defined as: systolic blood pressure \>160 mmHg or …