Early Detection of Cardiac Impairment and Prediction of RV Hypertrophy in Patients With CTD

Inclusion Criteria for CTD with RVH * Age between 18-80 years old. * Definite connective tissue diseases diagnosis. * Echocardiography demonstration (later confirmed by CMR) of a hypertrophic RV when maximal end-diastole RV wall thickness \>4 mm due to CTD Inclusion Criteria for CTD without RVH * Age between 18-80 years old. * Definite connective tissue diseases diagnosis. * Echocardiography demonstration (later confirmed by CMR) that maximal end-diastole RV wall thickness ≤4 mm Inclusion Criteria for Control group: * Absence of known systemic diseases * Normal examinations * Age between 18-80 years old. * Providing written informed consent Exclusion Criteria: * Age \<18 years old or \>80 years old * Documented coronary artery disease or prior angiography for coronary artery disease (\>50% stenosis). * Patients with known congenital heart disease or other systemic diseases that might induce RVH. * Patients with standard metallic contraindications to CMR or an estimated glomerular filtration rate \< 30 ml/min/1.73 m2.