RecruitingNot Applicable

Transcranial Direct Current Stimulation (tDCS) Neuromodulation of Executive Function Across Neuropsychiatric Populations

United States600 participantsStarted 2014-09

Plain-language summary

In the current study, the investigators aim to understand the role of transcranial direct current stimulation (tDCS) in improving executive function across neuropsychiatric populations known to have deficits in this cognitive domain.

Who can participate

Age range18 Years – 65 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion criteria

✓. Male and female outpatients 18-65 years of age
✓. A diagnosis of traumatic brain injury, major depressive disorder, bipolar disorder, schizophrenia, attention deficit hyperactivity disorder, borderline personality disorder and substance use disorders meeting the Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (DSM-5) criteria.

Exclusion criteria

✕. Contraindication to tDCS: history or epilepsy, metallic implants in the head and neck, brain stimulators, vagus nerve stimulators, shunts, pacemakers, pregnancy.
✕. Active substance dependence (except for tobacco and cannabis).
✕. Pregnant or nursing females.
✕. Inability to participate in testing procedures.
✕. Additional exclusion criteria for healthy controls:
✕. Diagnosis of psychiatric of neurological disorder
✕. Ongoing treatment with any psychotropic medications.

What they're measuring

Change in N-Back Task

Timeframe: Baseline to Post-Treatment, 1 Week

Trial details

NCT IDNCT04296604

SponsorMassachusetts General Hospital

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2026-04

Contact for this trial

Joan Camprodon, MD, PhD, MPH

6177265348

View on ClinicalTrials.gov More Traumatic Brain Injury trials