CompletedNot Applicable

Extending CPAP Therapy in Stable Preterm Infants to Increase Lung Growth and Function

United States100 participantsStarted 2020-01-10

Plain-language summary

This is a study to see if an extra 2 weeks of continuous positive airway pressure (CPAP) in stable preterm infants in the neonatal intensive care unit (NICU) can cause increased lung growth and lung function in the infants as measured at 6 months of age by pulmonary function testing.

Who can participate

Age range1 Day – 12 Weeks

SexALL

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Inclusion criteria

✓. Infants born at \>24 to ≤ 32 weeks gestation
✓. Treated with CPAP for ≥ 24 hours for respiratory distress (either as initial therapy or following extubation)

Exclusion criteria

✕. Significant congenital heart disease
✕. Major malformations
✕. Chromosomal anomalies
✕. Culture proven sepsis at consent
✕. Complex maternal medical conditions
✕. Clinical instability
✕. Multiple gestations \> twins
✕. \<3rd or \>97th percentile for weight85

What they're measuring

Alveolar Volume

Timeframe: 4 - 8 months of age

Trial details

NCT IDNCT04295564

SponsorCynthia McEvoy

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2023-09-18

Results submitted2024-11-21

View on ClinicalTrials.gov More Neonatal trials