The study should evaluate the biological distribution of 99mTc-1-thio-D-glucose in patients with Hodgkin Lymphoma and Non Hodgkin Lymphoma. The primary objective are: 1. To assess the distribution of 99mTc-1-thio-D-glucose in normal tissues and tumors at different time intervals. 2. To evaluate dosimetry of 99mTc-1-thio-D-glucose. 3. To study the safety and tolerability of the drug 99mTc-1-thio-D-glucose after a single injection in a diagnostic dosage. The secondary objective are: 1\. To compare the obtained 99mTc-1-thio-D-glucose SPECT imaging results with the data of CT imaging and/or 18F-FDG positron emission tomography (PET) and immunohistochemical (IHC) studies in Lymphoma patients.
Age range
18 Years – 70 Years
Sex
ALL
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A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
Gamma camera-based whole-body 99mTc-1-thio-D-glucose uptake value (percent)
Timeframe: 24 hours
SPECT-based 99mTc-1-thio-D-glucose value in tumor lesions (counts)
Timeframe: 6 hours
SPECT-based 99mTc-1-thio-D-glucose uptake value (counts)
Timeframe: 6 hours
Tumor-to-background ratio (SPECT)
Timeframe: 6 hours