CompletedNot Applicable

Recovering Arm Function in Chronic Post-stroke Patients Using Combined HD-tDCS and Virtual Reality Therapy

France58 participantsStarted 2021-02-01

Plain-language summary

The study aims to determine the added value of combining high-definition transcranial direct current stimulation (HD-tDCS) in a rehabilitation program based on virtual reality therapy (VRT) to potentiate the effects on neuroplasticity and further improve functional recovery of the arm in chronic stroke patients.

Who can participate

Age range

18 Years – 90 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Patient aged 18 to 90 * Patient with more than 3 months of a first cerebrovascular accident whatever the aetiology * Patient with paresis of the upper extremity (FM-UE ≥ 15) Exclusion Criteria: * Failure to collect written informed consent after a period of reflection * Not be affiliated with a French social security scheme or beneficiary of such a scheme * Major deficit of the upper extremity (FM-UE \<15) * History of epilepsy * Presence of a pacemaker or a metallic object implanted in the head * Pregnant or lactating * Severe neglect or attention deficit disorder (omission of more than 15 bells in the Bell's test) * Severe cognitive impairment (Mini Mental Score \<24) * Aphasia with impairment of understanding (Boston Aphasia Quotient \<4/5) * Under guardianship or curatorship * Protected by law

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

Change in Functional Motor capacity of the upper extremity

Timeframe: Change from Baseline at Day 21(after intervention) and 3 months after day 21

Change in Functional Motor capacity of the upper extremity

Timeframe: Change from Day 21 at 3 months (retention)

Change in Motor deficit of the upper extremity

Timeframe: Change from Baseline at Day 21 (after intervention) and 3 months after day 21

Change in Motor deficit of the upper extremity

Timeframe: Change from Day 21 at 3 months (retention)

Change in Hand dexterity

Timeframe: Change in Baseline at Day 21 (after intervention) and 3 months after day 21

Change in Hand dexterity

Timeframe: Change in Day21 at 3 months (retention)

Trial details

NCT IDNCT04291573

SponsorUniversity Hospital, Montpellier

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2025-03-26

View on ClinicalTrials.gov More Chronic Post Stroke Individuals trials

Plain-language summary

Who can participate

Age range

18 Years – 90 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

What they're measuring

Change in Functional Motor capacity of the upper extremity

Timeframe: Change from Baseline at Day 21(after intervention) and 3 months after day 21

Change in Functional Motor capacity of the upper extremity

Timeframe: Change from Day 21 at 3 months (retention)

Change in Motor deficit of the upper extremity

Timeframe: Change from Baseline at Day 21 (after intervention) and 3 months after day 21

Change in Motor deficit of the upper extremity

Timeframe: Change from Day 21 at 3 months (retention)

Change in Hand dexterity

Timeframe: Change in Baseline at Day 21 (after intervention) and 3 months after day 21

Change in Hand dexterity

Timeframe: Change in Day21 at 3 months (retention)