A Study of Local Administration of Autologous Mesenchymal Stromal Cells in Dysphonic Patients With Vocal Fold Scarring

Inclusion Criteria: * Patients between 18-65 years with VF scarring and severe voice problems, such as permanent severe hoarseness, complete aphonia or severe voice strain during speech (\>1 year) where other treatments have proven ineffective and no alternative treatment is possible. * No alternative treatment ongoing or planned (phonosurgery with augmentation implantation, voice therapy or other medical treatment). Exclusion Criteria: * Active treatment of laryngeal disorder, inflammatory condition of the larynx, or laryngeal/VF papilloma. * Diagnosed or suspicion of local malignancy or other malignancies, Disease-free period of \>5 years after malignant disease (\>10 years for local laryngeal cancer). * Smokers. * Large scar defects. * Pregnant or nursing (lactating) women. * Serological evidence of infection with HIV, HBV, HCV, HTLV and/or syphilis. * Active ongoing local or systemic infections. * Ongoing immune suppressive treatment.