This study collects data on microbiological, genetic and environmental factors, as well as lung function parameters (e.g. spirometry, body plethysmography, lung-MRI) to assess the complex interaction of predisposing risk factors for impaired lung development and respiratory diseases.
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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Change in Multiple Breath Washout
Timeframe: Every third year from the age of 4-6 weeks/1 year till >16 years.
Change in Spirometry
Timeframe: Every third year from the age of 4-6 weeks/1 year till >16 years
Change in Body plethysmography
Timeframe: Every third year from the age of 4-6 weeks/1 year till >16 years.
Change in Magnetic Resonance Imaging (MRI)
Timeframe: At the age of 4-6 weeks, 1, 3, 6, 9, 12, 15 and >16 years.
Change in Nasal swabs
Timeframe: At the age of 4-6 weeks, 1, 3, 6, 9, 12, 15 and >16 years.
Change in Weekly swabs
Timeframe: Weekly from the visit at the age of 8-12 weeks till the age of 1 year.
Swabs during respiratory infection
Timeframe: Any timepoint between the visit at the age of 4-6 weeks till the age of 1 year.