Mitomycin-C Injection Therapy in Refractory Esophageal Stricture

Inclusion Criteria: * aged more than 29 year and less than 75 year * refractory benign esophageal stricture who had the symptoms of dysphagia score suggested by Mellow et al greater than 3 (0: able to eat a normal diet, 1: able to eat some solid food, 2: able to eat some semi-solids only, 3: able to swallow liquids only, 4: complete dysphagia) Exclusion Criteria: Patients who have at least one of following conditions were excluded from our study * malignant esophageal stricture * multiple sites of esophageal stricture * pregnant or breast feeding status * clinical deterioration not tolerated to endoscopic procedures * esophageal motility disorders * esophageal leakage or fistula * hypersensitivity to mitomycin C * bleeding tendency due to thrombocytopenia or clotting disorders