UnknownPhase 4

Perioperative Continuation of Metformin Therapy in Patients With Typ 2 Diabetes Mellitus Undergoing Non-cardiac Surgery

400 participantsStarted 2020-02

Plain-language summary

Evaluation of the effect of peri-operative continuation of oral metformin therapy on the incidence of perioperative hyperglycemia compared to standard preoperative cessation of oral metformin therapy 24h before surgery.

Who can participate

Age range18 Years – 99 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Age 18-99 years * Diabetes Mellitus Typ 2 * Oral metformin therapy * Non cardiac-surgery * Informed consent Exclusion Criteria: * Insulin therapy * Ambulatory surgery * Preoperative therapy with glucocorticoids (prednisolon or equivalent ≥ 5mg/day for more than 7 days) * Planned postoperative ICU-stay * Advanced renal insufficiency (eGFR \< 45ml/kg/min) * Advanced liver cirrhosis or failure (Child-Pugh B or C) * Alcohol abuse * Pregnancy, * Perioperative administration of contrast dye

What they're measuring

Incidence of Perioperative Hyperglycemia

Timeframe: 24 hours pre-op until 24 hours post-op

Trial details

NCT IDNCT04284722

SponsorKepler University Hospital

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2021-02

Contact for this trial

Matthias Noitz, MD

+43 (0)5 7680 83 - 78171 matthias.noitz@kepleruniklinikum.at

View on ClinicalTrials.gov More Hyperglycemia trials