UnknownNot Applicable

Cell Block Immunohistochemistry in Effusion Cytology

Egypt100 participantsStarted 2020-04-01

Plain-language summary

Cytology is usually the first step in investigating serous effusions, to either detect or exclude an underlying malignancy. This study will try to answer the need for improved diagnostic yield of cytologic examination by cell block technique and immunohistochemical testing of three markers which are EZH2, Claudin-4 and MOC-31.

Who can participate

SexALL

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Inclusion Criteria: * all cases with serous effusion of unknown aetiology including ascites, pleural or pericardial effusions. Exclusion Criteria: * No exclusion criteria from the histopathologist perspective, i.e. all cases that undergone diagnostic aspiration are eligible for the study.

What they're measuring

Diagnostic performance of EZH2

Timeframe: within 48 hours

Diagnostic performance of claudin4

Timeframe: within 48 hours

Diagnostic performance of MOC-31

Timeframe: within 48 hours

Trial details

NCT IDNCT04279327

SponsorAssiut University

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2021-04

Contact for this trial

Aliaa EM Mahmoud, MSc

+201007508736 aliaa.elhosainy88@yahoo.com

View on ClinicalTrials.gov More Effusion Pleural trials