CompletedEarly Phase 1

Decreased Neuraxial Morphine After Cesarean Delivery

United States87 participantsStarted 2020-09-09

Plain-language summary

The purpose of this study is to compare 50mcg to 150mcg morphine in epidural for the goal of decreasing side effects of medication with lower dose in patients who receive a QL block

Who can participate

Sex

FEMALE

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * All women presenting for scheduled cesarean delivery who desire a QL block Exclusion Criteria: * Women with pregnancies complicated by preeclampsia * Women with pregnancies complicated by insulin-treated diabetes * Women with pregnancies complicated by placental abnormalities * Women with pregnancies complicated by a history of opioid use disorder

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

Outcome of side effects of intervention: pruritus

Timeframe: One assessment during hospital stay - up to postoperative day 2 (2 days following cesarean delivery)

Outcome of side effects of intervention: nausea

Timeframe: One assessment during hospital stay - up to postoperative day 2

Outcome of side effects of intervention: urinary retention

Timeframe: One assessment during hospital stay - up to postoperative day 2 (2 days following cesarean delivery)

Trial details

NCT IDNCT04279054

SponsorUniversity of Alabama at Birmingham

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2023-07-05

View on ClinicalTrials.gov More Anesthesia trials

Who can participate

Sex

FEMALE

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

What they're measuring

Outcome of side effects of intervention: pruritus

Timeframe: One assessment during hospital stay - up to postoperative day 2 (2 days following cesarean delivery)

Outcome of side effects of intervention: nausea

Timeframe: One assessment during hospital stay - up to postoperative day 2

Outcome of side effects of intervention: urinary retention

Timeframe: One assessment during hospital stay - up to postoperative day 2 (2 days following cesarean delivery)