CompletedNot Applicable

microRNA 155 Levels and Periodontal Microflora (Bacteria and Virus) in Preeclampsia.

India445 participantsStarted 2015-08-01

Plain-language summary

Preeclamptic women with and without chronic periodontitis were recruited for the study. Subgingival plaque samples and placental tissue samples(postpartum) were obtained from the participants for the microbial analysis(bacteria, viruses) and MIR155 levels and comparison was done among groups. this study was designed in order to evaluate the role of periodontal microorganisms in preeclampsia and to find compare the MIR155 levels among participants, so as to check its importance as a biomarker for inflammatory disease like preeclampsia.

Who can participate

Age range18 Years – 35 Years

SexFEMALE

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Pregnant women within the age group of 18-35 years with single gestation, having ≥ 20 natural teeth, who did not receive periodontal treatment in last six months and willing to participate in the study were included for the investigation. Exclusion Criteria: * Pregnant women with current use of any form of tobacco, history of alcohol consumption and systemic medications were excluded from the study.

What they're measuring

Viruses, Bacteria and placental mir155 in Chronic Periodontitis and Preeclampsia

Timeframe: it took approximately 15 minutes to collect samples for DNA extraction.

Trial details

NCT IDNCT04277390

SponsorMeenakshi Ammal Dental College and Hospital

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2018-08-20

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