The aim of the study is to characterize paraffin oil induced granulomatous disease. We will investigate pathogenesis and natural history of paraffin disease. Subsequently, through further translational studies, we intend to identify novel treatments to be tested in future randomized clinical trials.
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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Number of patients with concentration of ionized calcium in plasma above normal range = Hypercalcemia
Timeframe: at first examination or developed during observation period until 2025
Number of patients with concentration of parathyroid hormone PTH in plasma below normal range
Timeframe: at first examination or developed during observation period until 2025