Effect of Cassia Cinnamon on Arterial Stiffness Parameters in Patients With Type 2 Diabetes Mellitus

Inclusion Criteria: * Written informed consent prior to the beginning of enrollment * Men and women 40 to 65 years old * Diagnosis of type 2 diabetes mellitus according to the American Diabetes Association criteria * Fasting plasma glucose ≥ 126 mg/dl (7.0 mmol/L) at least 8 h of fasting * Plasma glucose ≥ 200 mg/dl (11.1 mmol/L) 2 hours after oral glucose tolerance test * HbA1c ≥ 6.5 % (48 mmol/mol) * Plasma glucose ≥ 200 mg/dl (11.1 mmol/L) in a random glucose test with typical symptoms of hyperglucemia or hyperglycemic crisis. Exclusion Criteria: * HbA1c \< 6.5 % or \> 10 % or fasting glucose plasma \> 250 mg/dl * Total serum cholesterol ≥ 240 mg/dl * Triglycerides ≥ 400 mg/dl * History of allergy to any of the components used in the study * Consumption of additional drugs with known effects on glucose and lipids metabolism and weight reduction * History of cardiovascular disease, blood abnormalities and/or kidney, pancreatic or thyroid disease * Childbearing and breastfeeding women * History of smoking within 12 months prior to beginning of study * History of drug abuse and alcoholism * Pacemaker bearing or any other permanent bioelectronic device that could modify or interfere with electrical bioimpedance tests