UnknownNot Applicable

Spontaneous Antigenemia in Loiasis

Cameroon60 participantsStarted 2020-01-23

Plain-language summary

This prospective study will enroll and follow 60 loiasis patients with high worm burden to monitor the spontaneous release of filarial antigen in peripheral blood. This study will define the cross-reactive antigen profile of persons with spontaneous loiasis antigenemia, and determine whether it varies with time.

Who can participate

Age range18 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Ability to give informed consent * Loiasis Mf count \> 20,000 Mf/mL * Resident of study area * No evidence of severe or systemic comorbidities * Consent to storage of blood samples for future study Exclusion Criteria: * Subject plans to move from the study area during subsequent 12 months

What they're measuring

prevalence of specific cross-reactive L. loa antigens at baseline

Timeframe: 1 day

Trial details

NCT IDNCT04258670

SponsorWashington University School of Medicine

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2021-05

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