Safety and Feasibility of Sutureless Pars-plana Vitrectomy in Sub-Tenon Anesthesia

Inclusion Criteria: * Age over 40 years * Presence of a clinical condition that requires surgical treatment with vitrectomy and does not necessarily require general anesthesia (retinal detachment, endophthalmitis, vitreous hemorrhage, after silicone oil surgery, vitreomacular traction, epiretinal gliosis, macular holes, subretinal bleeding, lens luxation). * The medical indication for vitrectomy is not linked to study participation. Not until the patient has consented to the vitrectomy (standardized information forms) potential study subjects will be approached to participate in the clinical trial. * Willingness to participate in the clinical trial * Understanding the objectives of the clinical trial and the study process * Signed informed consent form Exclusion Criteria: * Concomitant diseases of the eye * State after filtering glaucoma operations * Distinct corneal opacities, which make the examination considerably more difficult * Complicated proliferative vitreoretinopathy * Lack of understanding of the study, its objectives and study conduct * Psychiatric diseases * Pregnancy * Simultaneous participation in another clinical trial