The following study has as main objective to evaluate whether the use of I-ONE® therapy can reduce post-operative pain thanks to the modulation of inflammation in patients with bone bruise on the knee after anterior cruciate ligament (ACL) injury if applied 15 days before and 60 days after ACL reconstruction surgery for 4 hours a day compared to a control group (no-treatment). Both groups will be able to take anti-inflammatory drugs for pain control as per normal clinical practice. The secondary objective of the study are: quantify the reduction in the size of the bone bruise area, improving the level of knee function and the amount of anti-inflammatory drugs used in the aforementioned patients in the postoperative period compared to a control group.
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Visual Analogue Scale
Timeframe: 24 months
Objective evaluation of the International Knee Documentation Committee
Timeframe: 24 months
Level of Tegner activity
Timeframe: 24 months
Whole-Organ Magnetic Resonance Imaging Score (WORMS) of the knee in osteoarthritis.
Timeframe: 24 months
Monitoring of the intake of anti-inflammatory drugs
Timeframe: 24 months