Therapeutic treatment is yet available for declining memory, which is an impairment affecting the quality of life for many older adults and patients with cognitive impairment. Cognitive training with an immersive video game promises to drive hippocampal-cortical plasticity and associated gains that can restore memory capability or provide therapeutic treatment for memory deficits.
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MDT Change in Mnemonic Discrimination
Timeframe: baseline immediately before and post-assessment immediately after training regimen is completed
WALK Change in Recall
Timeframe: baseline immediately before and post-assessment immediately after training regimen is completed
Changes in Volumetric-based Brain Morphometry Associated With Training-induced Changes in Mnemonic Discrimination
Timeframe: during collection of Outcome 1, baseline immediately before and post-assessment immediately after training regimen is completed
Changes in Task-based Cortical Functional Connectivity Associated With Training-induced Changes in Mnemonic Discrimination
Timeframe: during collection of Outcome 1, baseline immediately before and post-assessment immediately after training regimen is completed