SuspendedPhase 3

The SToICAL Study - The Soft Tissue Injection of Corticosteroid And Local Anaesthetic Study

Stopped: Standard of Care change impacted recruitment

United Kingdom100 participantsStarted 2020-02-26

Plain-language summary

Some hand conditions can be treated with a steroid injection. Some doctors mix the steroid with local anaesthetic in the hope that the patient will experience less pain after the injection. Some doctors do not do this. It is not known if adding local anaesthetic to the steroid improves patient's pain after the injection. The overall aim of the study is to see whether using local anaesthetic in the steroid injection makes a difference to patients' pain. If the study shows that using local anaesthetic improves patients' pain then the investigators should continue using it. If not, the investigators should stop giving patients unnecessary medication, which would also save the NHS time and money.

Who can participate

Age range

18 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Male or female ages \>/= 18 years * A clinical diagnosis of trigger finger, de Quervains tenosynovitis or carpal tunnel syndrome made by a consultant physician. * Treatment with corticosteroid injection is recommended by the doctor and agreed by the patient * Patient is willing and able to give informed consent for participation in the study Exclusion Criteria: * Previous surgery for the condition being treated at the desired location of injection * Previous steroid injection for the condition being treated at the desired location of injection * Clinical suspicion of local or systematic sepsis or infection * History of hypersensitivity to the corticosteroid or local anaesthetic * Pregnant or breast-feeding females * Unable to understand and complete self-report questionnaires written in English

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

Pain visual analog scale scores at 1 hour

Timeframe: 1 hour

Trial details

NCT IDNCT04253457

SponsorUniversity Hospital Plymouth NHS Trust

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2025-01-23

View on ClinicalTrials.gov More Carpal Tunnel Syndrome trials