Patients with irritable bowel syndrome (IBS) often benefit from dietary changes. The effect of a gluten-free diet (GFD) on clinical symptom improvement and psychological well-being will be checked in patients with IBS. In addition, the stimulatory potential of gluten on peripheral blood monocytes will be determined. Responders will be provoked with gluten containing bars or placebo bars to confirm the diagnosis of non-celiac glutensenstitivity.
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Determination of inflammatory Stimulation of monocytes after gluten exposure
Timeframe: six weeks
Differences in Stimulation of inflammatory Parameters between healthy controls and patients with irritable bowel disease (IBD)
Timeframe: six weeks