CompletedNot Applicable

A Study of HD-tDCS and Cognitive Training to Improve Cognitive Function in MCI

United States8 participantsStarted 2021-01-25

Plain-language summary

The primary objective of this project is to assess the feasibility of multi-field, extended HD-tDCS (MFE-HD-tDCS) with simultaneous computerized CT as a viable intervention to improve cognitive function in patients with MCI. This double-blinded, randomized pilot clinical trial of repetitive daily HD-tDCS/sham HD-tDCS, administered in combination with CT to subjects with MCI in 3 monthly blocks of 5 daily sessions for a total of 15 sessions will enroll 8 participants.

Who can participate

Age range50 Years – 90 Years

SexALL

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Inclusion criteria

✓. Age ≥50-90 years
✓. Willing and able to undergo all procedures
✓. Retains decisional capacity at initial visit
✓. Meets criteria for MCI, amnestic type (Petersen, 2004).

Exclusion criteria

✕. Significant kidney injury requiring hemodialysis
✕. Automatic Internal Cardiac Defibrillator (AICD) or Pacemaker
✕. Significant congestive heart failure
✕. History of clinically significant ischemic or hemorrhagic stroke, or lacune or infarct considered by radiologist likely to cause or contribute significantly to cognitive symptoms
✕. History of thalamic lacunar stroke
✕. Modified Hachinski Ischemia Score \>4 points
✕. History of seizure disorder requiring medication
✕. History of brain surgery (for seizure disorder, aneurysms, or benign/malignant tumor)

What they're measuring

Assess the Feasibility of MFE-HD-tDCS Plus Simultaneous Computerized CT as a Viable Intervention by Measuring Consent Rates and Treatment Completion

Timeframe: 6 months

Trial details

NCT IDNCT04246164

SponsorMedical College of Wisconsin

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2023-02-23

Results submitted2024-04-22

View on ClinicalTrials.gov More Mild Cognitive Impairment trials