If Chronic Gallbladder Diseases Increase the Incidence of PEC

Inclusion Criteria: * ERCP patients with gallbladder in situ Exclusion Criteria: * Acute cholecystitis before surgery * Gallbladder has been removed * Gastrointestinal reconstruction * Unwillingness or inability to consent for the study * Unstable vital signs Coagulation dysfunction (INR\>1.5) * Low peripheral blood platelet count (\<50×10 \^9 / L) or using anti-coagulation drugs * Preoperative coexistent diseases: acute pancreatitis, GI tract hemorrhage, severe liver disease (such as decompensated liver cirrhosis, liver failure and so on), septic shock Biliary- duodenal fistula confirmed during ERCP * Pregnant women or breastfeeding