CompletedPhase 1/2

Core Decompression With or Without Cement Packing for ONFH

37 participantsStarted 1997-01-01

Plain-language summary

Osteonecrosis of the femoral head (ONFH) is difficult to treat as collapse frequently occurs after core decompression (CD). This may be due to the failure to provide structural support during revascularization and healing. Reports of polymethylmethacrylate (PMMA) packing of the femoral head after CD for ONFH have noted favorable results. This study was undertaken to determine whether the addition of PMMA packing to CD provides any benefit to progression-free survival (PFS) and conversion to total hip arthroplasty-free survival (CFS). Secondary objectives were to assess for differences in functional outcomes and predictive factors for progression of the disease.

Who can participate

Age range14 Years

SexALL

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Inclusion Criteria: * Association Research Circulation Osseous (ARCO) Stage I and II ONFH diagnosed using MRI and radiographic imaging Exclusion Criteria: * pre-existing collapse, subchondral fracture or degenerative changes of the hip

What they're measuring

Progression Free Survival (PFS)

Timeframe: 5 years

Trial details

NCT IDNCT04233125

SponsorUniversity of Minnesota

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2005-01-01

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