Cannabis Impairment Detection Application (CIDA)

Inclusion Criteria: * Men and women 18 to 50 years of age in good health (21 to 50 for alcohol arm) * Valid US driver's license and have been licensed driver for two years * Restrictions on driver's license limited to vision correction only * Drive at least three times per week * Must be able to drive without special or non-standard equipment * Must be able to attend three morning daytime study visits lasting approximately 5 to 6 hours * Must be willing to abstain from alcohol use in the day prior to their study appointments * Must be willing to abstain from use of their own cannabis while enrolled in the study * Live within 1-hour driving radius of National Advanced Driving Simulator (NADS) * Must currently use cannabis at least once every three months and no more than four times per week (must be current user) * Peripheral veins suitable for venipuncture * Blood pressure within clinically normal range * If invited to complete alcohol arm: Must be considered a light or moderate drinker according to Quantity-Frequency-Variability Scale (QFV) or, if a heavy drinker, not drink more than 1-2 times a week and not have a modal quantity of 5-6 drinks Exclusion Criteria: * Females who are pregnant or test positive for pregnancy or are breastfeeding * Any known sleep disorders, or family history of sleep disorders * Any neurological or pulmonary disorders (or taking medications for such) * Any psychiatric disorder (or taking medications for such) * Any eating disorders * Recent (p…