Development of Risk Score Model and Decision Tree Algorithm for Predicting Infections With CRKp in Colonized Patients

Inclusion Criteria: * All adult (≥18 years) patients having rectal colonization or history of previous invasive infection with CRKp * Group 1 cases are constituted by one BSI episode or non-bactereamic invasive infection episode (eg. pneumonia, intra-abdominal infection or urinary tract infection) with CRKp and a positive rectal swab screening or invasive infection (e.g. pneumonia, urinary tract infection and BSI) with CRKp within 90 days before identification of index BSI or other invasive infection with CRKp * Group 2 cases who are colonized with CRKp or had invasive infection (e.g. pneumonia, urinary tract infection and BSI) with CRKp within 90 days before identification of index BSI or other types of invasive infection with any bacteria other than CRKp and develop subsequent BSI or non-bactereamic invasive infection with these bacteria * Group 3 cases involve the colonized patients with CRKp who do not develop subsequent BSI or other invasive infections with CRKp or any other bacteria Exclusion Criteria: * \<18 years old patients * Palliative patients * Pregnant and breast-feeding patients * Patients who cannot be followed through 90-days. * Patients who are de-colonized with antibiotics, prebiotics-probiotics or fecal microbiota transplantation