CompletedNot Applicable

Periodontal Regeneration Versus Tooth Extraction and Replacement Denture in Teeth With Periodontal Hopeless Prognosis

Hong Kong50 participantsStarted 1998-06-01

Plain-language summary

Periodontal regeneration can change tooth prognosis and represents an alternative to extraction in teeth compromised by severe intrabony defects. The aim of this study is to compare periodontal regeneration (PR) with tooth extraction and replacement (TER) in a population with attachment loss to or beyond the apex of the root in terms of professional, patient reported and economic outcomes.

Who can participate

Age range18 Years – 60 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Good general health * Non-smokers or smokers with less than 20/day * Good oral hygiene (FMPS\<25%) * Good control of periodontitis (FMBS\<25%) * Good compliance with treatment * Presence of generalised stage III or IV periodontitis * Radiographic bone loss to the apex or beyond the apex of the root at at least one interdental aspect * Presence of severe clinical attachment level loss (\>10 mm) * Presence of clearly identifiable crest of bone in adjacent teeth * Lack of function due to hyper mobility * Vital or non-vital teeth Exclusion Criteria: * Medical contraindication to elective surgery * Poor oral hygiene * Incomplete control of periodontitis in the dentition * Inadequate compliance * Inability to provide informed consent

What they're measuring

Tooth or tooth replacement survival

Timeframe: 10 year

Occurrence and cost of management of recurrence

Timeframe: 10-year

Oral health related quality of life: OHIP-14 (Oral Health Impact Profile)

Timeframe: 10 years

Trial details

NCT IDNCT04227964

SponsorThe European Research Group on Periodontology (ERGOPerio)

Sponsor typeNETWORK

Study typeINTERVENTIONAL

Primary completion2014-12-31