CompletedPhase 3

Dual Trigger in the Final Oocyte Maturation in Poor Ovarian Responders

Lebanon140 participantsStarted 2018-07-11

Plain-language summary

This is a randomized controlled clinical trial to investigate the effect of dual trigger (hCG and GnRH agonist) on the final oocyte maturation compared to the standard hCG trigger in patients with poor ovarian reserve seeking IVF/ICSI treatment.

Who can participate

Age range18 Years – 44 Years

SexFEMALE

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Normal uterine cavity (as assessed by hysteroscopy or HSG). * Normal hormonal investigation: TSH, PRL. * Low ovarian reserve patients (AMH\<1.5ng/ml, AFC of 7 or less, 5 oocytes or less retrieved in a previous cycle) Exclusion Criteria: * Abnormal uterine cavity (Hysteroscopy or HSG) * Evidence of untreated endocrine disorders (abnormal TSH, prolactin, testosterone and androstenedione concentrations)

What they're measuring

Number of oocytes retrieved (oocyte collection rate)

Timeframe: 38 hrs

Number of mature oocytes (oocyte maturation rate)

Timeframe: 38 hrs

Trial details

NCT IDNCT04224818

SponsorAmerican University of Beirut Medical Center

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2019-08-20

View on ClinicalTrials.gov More Poor Ovarian Reserve trials