cfDNA in Diagnosis and Differential Diagnosis of Ovarian Endometriosis (NCT04220710) | Clinical Trial Compass
UnknownNot Applicable
cfDNA in Diagnosis and Differential Diagnosis of Ovarian Endometriosis
China390 participantsStarted 2019-08-20
Plain-language summary
Methylation detection of circulating free DNA to identify markers for diagnosis and differential diagnosis of ovarian endometriosis.
Who can participate
Age range
18 Years
Sex
FEMALE
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion criteria
. pathologically diagnosed as ovarian endometriosis;
. surgery was performed in PUMCH
Exclusion criteria
. patients with ovarian cancer:
. pathologically diagnosed as epithelial ovarian cancer;
. surgery was performed in PUMCH
. combined with gynecological benign tumors and other malignant tumors;
. combined with other systemic malignancies or malignancies history;
. pregnant patients (3) patients with other benign ovarian tumors:
. pathologically diagnosed as benign ovarian tumors but not ovarian endometriosis;
. surgery was performed in PUMCH
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1This trial is focused on using a blood-based DNA test called cfDNA methylation to diagnose ovarian endometriosis — could you explain how this approach might compare to the current standard diagnostic methods I'd likely go through, like laparoscopy or imaging?
2Since this trial lists an 'unknown' recruitment status, do you know whether it is still actively enrolling patients, and would it even be possible for me to participate at this stage?
3The study is measuring how well cfDNA methylation works at distinguishing ovarian endometriosis from other conditions — does that mean I might need to provide blood samples or undergo other tests as part of participation, and how would that fit into my current care schedule?
4Because this appears to be a diagnostic study rather than a treatment trial, does taking part mean I would still receive standard care and treatment for my symptoms, or could participation affect or delay any treatment decisions?
5Given that this trial is categorized under 'circulating free DNA' rather than a specific treatment phase, what would you say are the realistic benefits for me personally versus the potential value this research offers to future patients?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
The efficacy of cfDNA methylation in the diagnosis of ovarian endometriosis